Gu Kong Selected Research

sauristolactam

3/2011	The in vitro and in vivo anti-tumor effect of KO-202125, a sauristolactam derivative, as a novel epidermal growth factor receptor inhibitor in human breast cancer.
1/2010	KO-202125, a sauristolactam derivate, induces apoptosis to prevent KB human oral squamous carcinoma cells through inhibition of cyclooxygenase-2 expression.

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Gu Kong Research Topics

Disease

37	Breast Neoplasms (Breast Cancer) 01/2021 - 06/2004
35	Neoplasms (Cancer) 01/2021 - 01/2001
6	Neoplasm Metastasis (Metastasis) 01/2021 - 08/2002
5	Carcinogenesis 10/2019 - 11/2005
4	Hypoxia (Hypoxemia) 06/2013 - 03/2006
4	Squamous Cell Carcinoma (Epidermoid Carcinoma) 03/2010 - 12/2002
4	Fatty Liver 03/2009 - 04/2007
4	Fibrosis (Cirrhosis) 03/2009 - 11/2005
2	Uterine Cervical Neoplasms (Cancer of the Cervix) 03/2011 - 02/2009
2	Mouth Neoplasms (Oral Cancer) 03/2010 - 01/2010
2	Adenocarcinoma 12/2002 - 01/2001
2	Pancreatic Neoplasms (Pancreatic Cancer) 08/2002 - 01/2001
1	Turcot syndrome 05/2016
1	Chromothripsis 08/2015
1	Adenocarcinoma of Lung 06/2015
1	Hepatocellular Carcinoma (Hepatoma) 12/2014
1	Liver Neoplasms (Liver Cancer) 01/2011
1	Colonic Neoplasms (Colon Cancer) 03/2010
1	Ovarian Neoplasms (Ovarian Cancer) 02/2009

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 05/2015 - 08/2002
5	Biomarkers (Surrogate Marker)IBA 06/2019 - 11/2006
5	Estrogen ReceptorsIBA 01/2018 - 03/2006
4	Biological ProductsIBA 01/2020 - 08/2002
4	DNA (Deoxyribonucleic Acid)IBA 07/2015 - 12/2006
3	Tamoxifen FDA LinkGeneric 01/2018 - 12/2010
3	Transcription Factors (Transcription Factor)IBA 12/2016 - 07/2015
3	Estrogens (Estrogen)FDA Link 05/2015 - 05/2006
3	Pharmaceutical PreparationsIBA 03/2011 - 11/2008
3	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2010 - 08/2002
3	EnzymesIBA 01/2010 - 08/2002
2	Trastuzumab (Herceptin)FDA Link 10/2019 - 06/2019
2	LigandsIBA 06/2019 - 12/2006
2	Histones (Histone)IBA 10/2015 - 05/2006
2	Progesterone Receptors (Progesterone Receptor)IBA 05/2015 - 05/2006
2	Phenobarbital (Luminal)FDA Link 05/2015 - 06/2004
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2011 - 04/2007
2	KO 202125IBA 03/2011 - 01/2010
2	sauristolactamIBA 03/2011 - 01/2010
2	Phospholipids (Phosphatides)FDA LinkGeneric 02/2010 - 03/2009
2	LipidsIBA 02/2010 - 04/2007
2	AntigensIBA 01/2010 - 05/2006
2	Ethanol (Ethyl Alcohol)IBA 03/2009 - 09/2007
2	Phosphatidylcholines (Phosphatidylcholine)IBA 03/2009 - 06/2008
2	Carbon Tetrachloride (Tetrachloromethane)IBA 06/2008 - 11/2005
2	Valproic Acid (Depakote)FDA LinkGeneric 02/2008 - 04/2007
2	Bexarotene (LGD1069)FDA Link 12/2006 - 04/2005
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 08/2002 - 01/2001
1	Histone MethyltransferasesIBA 01/2021
1	Phosphotransferases (Kinase)IBA 10/2019
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 10/2019
1	Histone DemethylasesIBA 01/2018
1	Retinoblastoma-Binding Protein 2IBA 01/2018
1	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 04/2017
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 04/2017
1	ChromatinIBA 05/2016
1	APOBEC DeaminasesIBA 05/2016
1	Intergenic DNA (Junk DNA)IBA 01/2016
1	MethyltransferasesIBA 10/2015
1	Cyclin D1IBA 08/2015
1	p300-CBP-associated factorIBA 07/2015
1	Hormones (Hormone)IBA 05/2015
1	Small Interfering RNA (siRNA)IBA 01/2015
1	C.I. Solvent Yellow 56 (DEAB)IBA 06/2013
1	Aldehyde DehydrogenaseIBA 06/2013
1	ErbB Receptors (EGF Receptor)IBA 03/2011
1	Gefitinib (Iressa)FDA Link 03/2011
1	Messenger RNA (mRNA)IBA 03/2011
1	tolfenamic acidIBA 03/2011
1	Complementary DNA (cDNA)IBA 01/2011
1	Indicators and Reagents (Reagents)IBA 01/2011
1	3,3'-diindolylmethane (diindolylmethane)IBA 03/2010
1	p38 Mitogen-Activated Protein KinasesIBA 03/2010
1	5,5'-dibromo-1,1-bis(3'-indolyl)methaneIBA 03/2010
1	IsothiocyanatesIBA 03/2010
1	PhosphatidylglycerolsIBA 02/2010
1	Phosphatidic Acids (Phosphatidic Acid)IBA 02/2010
1	PhosphatidylserinesIBA 02/2010
1	Phosphatidylinositols (Phosphatidylinositol)IBA 02/2010
1	AntioxidantsIBA 01/2010
1	Nitroso CompoundsIBA 01/2010
1	CarcinogensIBA 01/2010
1	CarbohydratesIBA 01/2010
1	VitaminsIBA 01/2010
1	Vitamin E FDA LinkGeneric 01/2010
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2010
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2010
1	beta Carotene (Betacarotene)FDA Link 01/2010
1	NitratesIBA 01/2010
1	sulforaphaneIBA 08/2009
1	Phosphatidylethanolamines (Cephalins)IBA 03/2009
1	Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA 01/2009
1	SpermidineIBA 01/2009
1	PutrescineIBA 01/2009
1	trimethylenediamineIBA 01/2009
1	PolyaminesIBA 01/2009
1	NF-kappa B (NF-kB)IBA 11/2008
1	Paclitaxel (Taxol)FDA LinkGeneric 11/2008
1	Methotrexate (Mexate)FDA LinkGeneric 07/2008

Therapy/Procedure

9	Therapeutics 10/2019 - 02/2008
1	Aftercare (After-Treatment) 01/2018